Filizola Lab Members

Juan Carlos Mobarec

Graduate Student
Computational Biology Ph.D. Student
Mount Sinai School of Medicine-NYU

Mailing Address:

Dept. of Structural and Chemical Biology
Mount Sinai School of Medicine
Icahn Medical Institute Building
1425 Madison Avenue, Box 1677
New York, NY 10029-6574
Tel.: 212-659-5488
Fax: 212-849-2456
Email: juan.mobarec@mssm.edu

Research Interest

Homology modeling of GPCRs, protein-protein docking, protein movement-function relationship, rational drug design, protein-protein interactions, molecular dynamics, protein-ligand docking, protein adaptation to extreme environments, protein folding/unfolding and protein engineering.

Training and Education

Biotechnology Engineer, University of Chile 2005

B.Sc. Molecular Biotechnology, University of Chile 2001

Publications

Bortolato, A., Mobarec, J.C., Provasi, D., Filizola, M. "Progress in Elucidating the Structural and Dynamic Character of G-Protein Coupled Receptor Oligomers for Use in Drug Discovery" Current Pharmaceutical Design (2009), 15(35):4017-4025.

Mobarec, J.C., Sanchez, R., Filizola, M. "Modern Homology Modeling of G-Protein Coupled Receptors: Which Structural Template to Use?" Journal of Medicinal Chemistry (2009), 52 (16), 5207-5216. PubMed

Guo,W., Urizar, E., Kralikova,M., Mobarec,J.C., Shi, L., Filizola, M., Javitch, J.A. "Dopamine D2 Receptors Form Higher Order Oligomers at Physiological Expression Levels" The EMBO Journal (2008), 27(17):2293-304. PubMed | Faculty of 1000 Biology

Mobarec, J.C. & Filizola, M. "Advances in the Development and Application of Computational Methodologies for Structural Modeling of G-Protein Coupled Receptors" Expert Opinion on Drug Discovery (2008), 3(3):343-355. PubMed

Acosta, M.; Beard, S.; Ponce, J.; Vera, M.; Mobarec, J.C.; Jerez, C. A. "Identification of Putative Sulfurtransferase Genes in the Extremophilic Acidithiobacillus ferrooxidans ATCC 23270 Genome: Structural and Functional Characterization of the Proteins" Omics: The Journal of Integrative Biology (2005), 9(1): 13-29. PubMed