obtain a reliable basis
for the description of three-dimensional structures
of a given protein family using
homology modeling through selection of an optimal subset
of the protein family
whose structure would be determined experimentally;
and
aid in the search of
orthologs by matching two sets of sequences in three different ways.
The prioritization is established dynamically
as new sequences and new structures are
becoming available through ranking proteins by their value
in providing structural
information about the rest of the family set.
The matching can give a list of potential
orthologs or it can deduce an overall optimal matching
of two sets of sequences.
