Zeng, L., Zhang, Q., Gerona-Navarro, G., Moshkina, N., & Zhou, M.-M. (2008) Structural Basis of Site-Specific Histone Recognition by the Bromodomains of Human Coactivators PCAF and CBP/p300. Structure 16, 643-652. [PDF]

Ivanov, A.V., Peng, H., Yuchenko, V., Yap, K.L., Negorev, D.G., Schultz, D.C., Psulkowsky, E., Fredericks, W.J., White, D.E., Maul, G.G., Sadofsky, M.J., Zhou, M.-M., & Rauscher, F.J. (2007) PHD Domain-Mediated E3 Ligase Activity Directs Intramolecular Sumoylation of an Adjacent Bromodomain which is Required for Gene Silencing. Molecular Cell 28(5), 823-837. [PDF]

Sampath, S., Marazzi, I., Yap, K.L., Sampath, S., Krutchinskly, A., Mecklenbrauker, I., Vlale, A., Rudensky, E., Zhou, M.-M., Chait, B., & Tarakhovsky, A. (2007) Methylation of a Histone Mimic within the Histone Methyltransferase G9a Regulates Protein Complex Assembly. Molecular Cell, 27(4), 596-608. [PDF]

Pan, C., Mezei, M., Mujtaba, S., Muller, M., Zeng, L., Li, J.M., Wang, Z.Y., & Zhou, M.-M. (2007) Structure-Guided Optimization of Small Molecules Selectivity Inhibiting Human Immunodeficiency Virus 1 Tat Association with the Human Coactivator p300/CREB Binding Protein-Associated Facor. Journal of Med. Chem. 50, 2285-2288. [PDF]

Seet, B.T., Dikic, I., Zhou, M.-M., & Pawson, T (2006) Reading Protein Modifications with Interaction Domains. Nature Reviews Molecular Cell Biology 7, 473-483. [PDF]; featured by NRMCB From The Editors in July 2006.

Qian, C., Wang, X., Manzur, K., Sachchidanand, Farooq, A., Zeng, L., Wang, R. & Zhou, M.-M. (2006) Structural Insights of the Specificity and Catalysis of a Viral Histone H3 Lysine-27 Methyltransferase. J. Mol. Biol. 359, 86-96. [PDF]

Sachchidanand, Resnick-Silverman, L., Yan, S., Mutjaba, S., Liu, W.-J., Zeng, L., Manfredi, L., & Zhou, M-.M. (2006) Target Structure-Based Discovery of Small Molecules that Block Human p53 and CREB Binding Protein (CBP) Association. Chemistry & Biology 13, 81-90. [PDF]; featured by Nature Reviews in Drug Discovery in March 2006.

Qian, C., & Zhou, M.-M. (2006) SET Domain Protein Lysine Methyltransferases: Structure, Specificity and Catalysis. Cellular and Molecular Life Sciences 63, 2755-2763. [PDF]

Mujtaba, S., Zeng, L., & Zhou, M.-M. (2006) Dissecting Molecular Interactions and Regulation of p53 with Small Molecules. Cell Cycle 5, 2575-2578. [PDF]

Yap, K.L. & Zhou, M.-M. (2006) Structure and Function of Protein Modules in Chromatin Biology in Chromatin Dynamics in Cellular Function of Results & Problems in Cell Differentiation (B.C. Laurent, Ed.) Springer (USA), New York, NY, p. 1-23. [PDF]

Qian, C., Zhang, Q., Li, S., Zeng, L., Walsh, M.J., & Zhou, M.-M. (2005) Structure and Chromosomal DNA Binding of the SWIRM Domain. Nature Structural & Molecular Biology 12, 1078-1085. [PDF]

Zeng, L., Li, J., Muller, M., Yan, S., Mujtaba, S., Pan, C., Wang, Z., & Zhou, M.-M. (2005) Selective Small Molecules Blocking HIV-1 Tat and Coactivator PCAF Association. Journal of Am. Chem. Soc. 127, 2376-2377. [PDF]

Mujtaba, M., He, Y., Zeng, L., Yan, S., Plotnikova, O., Sachchidanand, Sanchez, R., Zeleznik-Le, N., Ronai, Z., & Zhou, M.-M. (2004) Structural Mechanism of the Bromodomain of the Coactivator CBP in p53 Transcriptional Activation. Mol. Cell, 13, 251-263. [PDF]

Yan, K.S., Yan, S., Farooq, A., Han, A., Zeng, L., & Zhou, M.-M. (2003) Structure and Conserved RNA Binding of the PAZ Domain. Nature 426, 469-474. [PDF]

Manzur, K., Farooq, A., Zeng, L., Plotnikova, O., Koch, A. W., Sachchidanand, & Zhou, M.-M. (2003) A Dimeric Viral SET Domain Methyltransferase Specific to Lys27 of Histone H3. Nature Struct. Biol. 10, 187-196. [PDF]

Mujtaba, S., He, Y. Zeng, L., Farooq, A., Carlson, J., Ott, M., Verdin, E., & Zhou, M.-M. (2002) Structural Basis of HIV-1 Tat Recognition by P/CAF Bromodomain, Mol. Cell 9, 575-586. [PDF]

Farooq, A., Chaturvedi, G., Mutjaba, S., Plotnikova, O., Zeng, L., Dhalluin, C., Ashton, R., & Zhou, M.-M. (2001) Solution Structure of ERK2 Binding Domain of MAPK Phosphatase MKP-3: Structural Insights into MKP-3 Activation by ERK2. Mol. Cell 6, 921-929. [PDF]

Dhalluin, C., Yan, K., Plotnikova, O., Lee, K.W., Zeng, L., Kuti, M., Mutjaba, S., Goldfarb, M.P., & Zhou, M.-M. (2000) Structural Basis of SNT PTB Domain Interactions with Distinct Neurotrophic Receptors. Mol. Cell 6, 921-929. [PDF]

Dhalluin, C., Carlson, J.,Zeng, L., He, C., Aggarwal, A.K., & Zhou, M.-M. (1999) Structure and Ligand of a Histone Acetyltransferase Bromodomain. Nature 399, 491-496. [PDF]

Zhou, M.-M., Huang, B., Olejniczak, E.T., Meadows, R.P., Shuker, S.B., Miyazak, M., Trub, T., Shoelson, S.E., & Fesik, S.W. (1996) Structural Basis of IL-4 Receptor Phosphopeptide Recognition by the IRS-1 PTB Domain. Nature Struct. Biol. 3, 388-393.

Zhou, M.-M., Ravichandran, K.S., Olejniczak, E.T., Petros, A.P., Meadows, R.P., Sattler, M., Harlan, J.E., Wade, W., Burakoff, S.J., & Fesik, S.W. (1995) Structure and Ligand Recognition of the Phosphotyrosine Binding Domain of Shc. Nature 378, 584-592.


Copyright © 2000 Zhou Laboratory. All rights reserved.