We seek self-motivated
individuals as Postdoctoral Fellows to study structure-function
of protein modular domains and enzymes in chromatin-mediated gene transcription
or the RNA interference pathway. Our laboratory is surrounded in a dynamic
research environment and equipped with state-of-the-art facilities for
biochemical research focused on three-dimensional structural analysis
of proteins with high-resolution NMR spectroscopy and X-ray crystallography.
Our NMR facility has one 600 MHz and one 500 MHz 4-channel Bruker NMR
spectrometers. We also have regular access to a cluster of 800 MHz and
900 MHz NMR systems with cryogenic probes at the New York Structural Biology
Center (NYSBC).
The selected individuals
will conduct structure-based functional analysis of proteins and structure-based
small molecule disovery. Requirements include a recent PhD degree in Chemistry
or Biochemistry with solid background and demonstrated experience in protein
biochemistry, molecular biology, protein NMR spectroscopy or X-ray crystallography.
Skills in recombinant protein techniques and computer programming are
preferred.
We offer competitive
salaries and excellent benefits along with the support and challenges
for performing cutting-edge science. Individuals with matching qualifications
should send a curriculum vitae, a statement of research interests,
and names of three references to:
Ming-Ming Zhou,
PhD
Professor and Chairman
Department of Structural & Chemical Biology
Mount Sinai School of Medicine
1425 Madison Avenue, Box 1677
New York, NY 10029-6574
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Phone: (212)
659-8652
Fax: (212) 849-2456
E-mail: Ming-Ming.Zhou@mssm.edu
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